Mood by Nedley Health is a specialized blend of SAMe and Saffron to assist in mood stabilization.*


Ships within 1 business day

Formulated with purpose

See supplement facts

Your best health in mind.

Mood by Nedley Health is a combination of SAMe and saffron commonly used in our Residential Depression and Anxiety Recovery Program™. This supplement can help to improve the brain’s ability to make serotonin and dopamine. It can assist in elevating mood, energy, improving memory, improving pain, improving inflammation, and increasing emotional stability during hormonal events.*

Add to bag

Real results for real people

I had been looking for something to help me thru this season of my life. This supplement has been a tremendous help!! I take it daily with the brain balance and have experienced such a difference in my overall mood and ability to cope with the daily. I am grateful for this product.
I’m 62 years old and have been taking Mood Balance for many months now. I’ve had no side effects. I’m taking two tabs daily. I’ve felt that my mood has been much improved consistently and my days of seeming brain fog have lifted. Thank you for this product. I was previously on lexapro off and on for several years and not happy with the side effects.
I tried antidepressants but the side effects were too harsh. I tried this and it was great! No side effects with a mood boost. I feel more grounded while still feeling all my emotions.
Read more reviews

Balance your nutrition

An imbalance in our brains can have significant side effects on our thoughts and feelings. Simple nutritional adjustments can cause remarkable changes in how we feel and behave. That’s why we formulated the Sleep, Mood, and Brain supplements that specifically focus on each neurotransmitter and its proper production in the brain.

Shop Signature Products


How does Mood by Nedley Health work?

Recent research has shown that saffron crocus has amazing anti-depressant properties, in part due to its serotonin production enhancing effects in the brain. [ii] Studies have shown saffron to be equivalent or superior to SSRIs in effectiveness when treating depression. Even more importantly, saffron does not have the unwanted emotional and sexual side effects of apathy or impulsivity. In combination with SAMe, these two ingredients can be powerful tools in combatting low serotonin levels and increasing overall mood stability. If you would like to learn more on how serotonin can effect your mental health, check out our article The Role of Serotonin in Treating Mental Health Disorders.

How long will it take for me to start seeing results?

Most individuals can notice positive results within 1-2 weeks. However, results may vary and we recommend consulting a healthcare professional if you are not seeing results or notice any abnormal changes.

Is Mood by Nedley Health safe?

Providing a healthier way to optimal brain health is our top priority. All Nedley Health products are manufactured in the United States with high-quality ingredients. The FDA provides guidelines on how to manufacture supplements called Current Good Manufacturing Processes, or cGMP, which our manufacturing facilities are required to follow.

How does my subscription work?

You pick how often you would like to receive your supplements, and we ship it you without you having to remember to place another order. If you would like to make any changes to your subscription, you can manage it from your subscription page, call our office, or chat with one of our customer representatives online. It’s that easy!

Is there HSA reimbursement?

To utilize your HSA eligible payment method, please call our office at 580-226-8007.

Shop Signature Supplements